Compound Detail
CHEMBL203607
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Basic Information
| ChEMBL ID | CHEMBL203607 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YNSHOHKDVJINOC-MRUKODCESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
466.7
MW (Da)
6.33
ALogP
5
HBA
1
HBD
72.8
PSA (Ų)
0.23
QED
1
Ro5 Violations
15
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein kinase C alpha type CHEMBL299 | Ki | 8.16 | 8.16 | 6.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein kinase C alpha type | Ki | = | 6.88 | nM | 8.16 | Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatid... | 16539391 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16539391 | 10.1021/jm0509391 | Protein kinase C alpha type | 1 |
Data from ChEMBL 36 via Core Engine