Compound Detail
CHEMBL2048337
EUDISTOMIN Y2 Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL2048337 |
| Name | EUDISTOMIN Y2 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DRIYUTQUFGEKEA-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
14
Publications
0
Known Names
Molecular Properties
367.2
MW (Da)
4.42
ALogP
3
HBA
2
HBD
66.0
PSA (Ų)
0.52
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Isocitrate lyase CHEMBL5359 | IC50 | 4.3 | 4.3 | 50200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Isocitrate lyase | IC50 | = | 50200.0 | nM | 4.3 | Inhibition of Candida albicans recombinant ICL assessed as formation of glyoxyla... | 22652254 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22652254 | 10.1016/j.bmc.2012.05.002 | Staphylococcus aureus | 1 |
| 22652254 | 10.1016/j.bmc.2012.05.002 | Bacillus subtilis | 1 |
| 22652254 | 10.1016/j.bmc.2012.05.002 | Micrococcus luteus | 1 |
| 22652254 | 10.1016/j.bmc.2012.05.002 | Salmonella typhimurium | 1 |
| 22652254 | 10.1016/j.bmc.2012.05.002 | Proteus vulgaris | 1 |
| 22652254 | 10.1016/j.bmc.2012.05.002 | Escherichia coli | 1 |
| 22652254 | 10.1016/j.bmc.2012.05.002 | Aspergillus fumigatus | 1 |
| 22652254 | 10.1016/j.bmc.2012.05.002 | Trichophyton rubrum | 1 |
| 22652254 | 10.1016/j.bmc.2012.05.002 | Trichophyton mentagrophytes | 1 |
| 22652254 | 10.1016/j.bmc.2012.05.002 | Candida albicans | 1 |
| 22652254 | 10.1016/j.bmc.2012.05.002 | A549 | 1 |
| 22652254 | 10.1016/j.bmc.2012.05.002 | Sortase A | 1 |
| 22652254 | 10.1016/j.bmc.2012.05.002 | Isocitrate lyase | 1 |
| 22652254 | 10.1016/j.bmc.2012.05.002 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine