Compound Detail
CHEMBL206122
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL206122 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RESVKOSPFKHQBK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
217.2
MW (Da)
2.20
ALogP
3
HBA
2
HBD
70.4
PSA (Ų)
0.81
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| GABA-A receptor; anion channel CHEMBL1907607 | Ki | 6.68 | 6.68 | 208.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| GABA-A receptor; anion channel | Ki | = | 208.0 | nM | 6.68 | Displacement of [3H]flumazenil from GABA-A receptor in rat cortical membranes | 16610795 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16610795 | 10.1021/jm058057p | GABA-A receptor; anion channel | 1 |
Data from ChEMBL 36 via Core Engine