Compound Detail
CHEMBL206725
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Basic Information
| ChEMBL ID | CHEMBL206725 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YNVSSYWJQVVFPB-LURJTMIESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
190.2
MW (Da)
-0.58
ALogP
4
HBA
3
HBD
103.9
PSA (Ų)
0.22
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 4.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| S-ribosylhomocysteine lyase CHEMBL5171 | Ki | 4.17 | 4.17 | 68000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| S-ribosylhomocysteine lyase | Ki | = | 68000.0 | nM | 4.17 | Inhibition of cobalt substituted Bacillus subtilis LuxS | 16686542 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16686542 | 10.1021/jm060047g | S-ribosylhomocysteine lyase | 5 |
Data from ChEMBL 36 via Core Engine