Compound Detail
CHEMBL2074582
PROSTAGLANDIN H2 Enter ChEMBL ID:
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CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@@H]2C[C@H]1OO2
Basic Information
| ChEMBL ID | CHEMBL2074582 |
| Name | PROSTAGLANDIN H2 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YIBNHAJFJUQSRA-YNNPMVKQSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
352.5
MW (Da)
4.02
ALogP
4
HBA
2
HBD
76.0
PSA (Ų)
0.32
QED
0
Ro5 Violations
12
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.42
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Solute carrier organic anion transporter family member 2A1 CHEMBL2073680 | Ki | 7.42 | 7.42 | 38.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Solute carrier organic anion transporter family member 2A1 | Ki | = | 38.2 | nM | 7.42 | TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cells | 8863817 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8863817 | - | Solute carrier organic anion transporter family member 2A1 | 1 |
Data from ChEMBL 36 via Core Engine