Compound Detail
CHEMBL20819
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL20819 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GFGNDIHZNWSGLN-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
347.5
MW (Da)
2.76
ALogP
4
HBA
1
HBD
44.8
PSA (Ų)
0.77
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(4) dopamine receptor CHEMBL219 | Ki | 6.5 | 6.5 | 316.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(4) dopamine receptor | Ki | = | 316.23 | nM | 6.5 | Binding affinity at cloned human Dopamine receptor D4 expressed in HEK 293 cells... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(96)00198-9 | D(4) dopamine receptor | 1 |
| - | 10.1016/0960-894X(96)00198-9 | D(2) dopamine receptor | 1 |
| - | 10.1016/0960-894X(96)00198-9 | Dopamine receptors; D2 & D4 | 1 |
Data from ChEMBL 36 via Core Engine