Compound Detail
CHEMBL208282
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Basic Information
| ChEMBL ID | CHEMBL208282 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YORONRYIMYLVCT-AQNSPSBUSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
392.6
MW (Da)
5.27
ALogP
4
HBA
2
HBD
66.8
PSA (Ų)
0.20
QED
1
Ro5 Violations
17
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cannabinoid receptor 1 CHEMBL3571 | EC50 | 4.8 | 4.8 | 15848.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cannabinoid receptor 1 | EC50 | = | 15848.93 | nM | 4.8 | Potency at CB1 receptor in rat brain by [35S]GTP-gamma-S binding assay | 16466915 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16466915 | 10.1016/j.bmcl.2006.01.101 | Cannabinoid receptor 1 | 2 |
Data from ChEMBL 36 via Core Engine