Compound Detail
CHEMBL2107254
CLOXAZOLAM 🧪 Phase II
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🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL2107254 |
| Name | CLOXAZOLAM |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | ZIXNZOBDFKSQTC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
2
Known Names
1
Indications
Molecular Properties
349.2
MW (Da)
3.48
ALogP
3
HBA
1
HBD
41.6
PSA (Ų)
0.86
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Racemic |
Indications
Anxiety
ATC Classification
N05BA22
cloxazolam
Level 1: NERVOUS SYSTEM
Level 2: PSYCHOLEPTICS
Activity Summary
Ki 1 meas. best 5.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Aldo-keto reductase family 1 member C3 CHEMBL4681 | Ki | 5.82 | 5.82 | 1500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Aldo-keto reductase family 1 member C3 | Ki | = | 1500.0 | nM | 5.82 | Discontinuous Radiometric Assay: Compounds may be evaluated as selective reversi... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.6019/CHEMBL4651402 | SARS-CoV-2 | 2 |
Data from ChEMBL 36 via Core Engine