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Compound Detail

CHEMBL2107408

GLYBUZOLE
🧪 Phase II
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🧪 Phase II
CC(C)(C)c1nnc(NS(=O)(=O)c2ccccc2)s1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL2107408
Name GLYBUZOLE
Phase Phase II
Structure Type MOL
InChI Key NMWQEPCLNXHPDX-UHFFFAOYSA-N

Known Names

AN 1324 AN-1324 Glibuzol Gludiase Glybuzole RP 7891 RP-7891
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
7
Known Names

Molecular Properties

297.4
MW (Da)
2.64
ALogP
5
HBA
1
HBD
72.0
PSA (Ų)
0.94
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Achiral

Extended Properties

Molecular Formula C12H15N3O2S2
MW 297.40
Aromatic Rings 2
Heavy Atoms 19
NP-Likeness -2.14

Activity Summary

IC50 1 meas. best 4.88

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
 IC50 4.88 4.88 13131.8 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Unchecked IC50 = 13131.8 nM 4.88 PubChem BioAssay. insulin secretion from INS-1E cells in the presence of 5 mM gl... -

Data from ChEMBL 36 via Core Engine