Compound Detail
CHEMBL2110839
DORASTINE 🧪 Phase II
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🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL2110839 |
| Name | DORASTINE |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | WCTGYFWVYBPRGF-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
3
Known Names
Molecular Properties
339.9
MW (Da)
4.23
ALogP
3
HBA
0
HBD
21.1
PSA (Ų)
0.71
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Activity Summary
IC50 2 meas. best 5.38
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.38 | 4.89 | 4201.4 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 4201.38 | nM | 5.38 | PubChem BioAssay. insulin secretion from INS-1E cells in the presence of 5 mM gl... | - |
| Unchecked | IC50 | = | 39905.66 | nM | 4.4 | PubChem BioAssay. tonic K+ channel activity under 0.1 mM glucose conditions in I... | - |
Data from ChEMBL 36 via Core Engine