Compound Detail
CHEMBL2111945
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2111945 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FXCTZFMSAHZQTR-PFJVYOFESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
247.2
MW (Da)
1.58
ALogP
5
HBA
1
HBD
68.1
PSA (Ų)
0.49
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Metabotropic glutamate receptor 1 CHEMBL3772 | IC50 | 5.82 | 5.82 | 1500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Metabotropic glutamate receptor 1 | IC50 | = | 1500.0 | nM | 5.82 | Inhibition of Quisqualate-Induced PI Hydrolysis measured in CHO Metabotropic glu... | 11087567 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11087567 | 10.1021/jm0009944 | Metabotropic glutamate receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine