Compound Detail
CHEMBL2114365
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2114365 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SGMZGZICZKFASN-ARLHGKGLSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
277.4
MW (Da)
2.26
ALogP
3
HBA
2
HBD
80.4
PSA (Ų)
0.76
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 6.11
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Aminopeptidase B CHEMBL2452 | Ki | 6.11 | 6.11 | 770.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Aminopeptidase B | Ki | = | 770.0 | nM | 6.11 | Competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified fr... | 2566685 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2566685 | 10.1021/jm00126a039 | Leucyl-cystinyl aminopeptidase | 2 |
| 2566685 | 10.1021/jm00126a039 | Aminopeptidase B | 1 |
Data from ChEMBL 36 via Core Engine