Compound Detail
CHEMBL2152562
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2152562 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VWSHPCDVNPNFRR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
302.4
MW (Da)
3.22
ALogP
3
HBA
3
HBD
74.6
PSA (Ų)
0.74
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate carboxypeptidase 2 CHEMBL1892 | IC50 | 8.15 | 8.15 | 7.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate carboxypeptidase 2 | IC50 | = | 7.0 | nM | 8.15 | Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate ... | 22642259 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22642259 | 10.1021/jm300488m | Glutamate carboxypeptidase 2 | 1 |
Data from ChEMBL 36 via Core Engine