Compound Detail
CHEMBL215570
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Basic Information
| ChEMBL ID | CHEMBL215570 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BXYNQZGYOBQGBJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
419.0
MW (Da)
1.77
ALogP
6
HBA
3
HBD
86.5
PSA (Ų)
0.51
QED
0
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | IC50 | 6.5 | 6.5 | 318.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | IC50 | = | 318.0 | nM | 6.5 | Antimalarial activity against chloroquine-resistant Plasmodium falciparum FcB1 | 16913719 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16913719 | 10.1021/jm0602763 | ScN2a | 3 |
| 16913719 | 10.1021/jm0602763 | Plasmodium falciparum | 1 |
| 16913719 | 10.1021/jm0602763 | MRC5 | 1 |
Data from ChEMBL 36 via Core Engine