Compound Detail
CHEMBL215698
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Basic Information
| ChEMBL ID | CHEMBL215698 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FJGMRQQOTBNXHV-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
364.4
MW (Da)
3.56
ALogP
4
HBA
5
HBD
114.7
PSA (Ų)
0.21
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.54
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| L6 CHEMBL614793 | IC50 | 4.54 | 4.54 | 29100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| L6 | IC50 | = | 29100.0 | nM | 4.54 | Cytotoxicity against rat L6 cells | 16913722 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16913722 | 10.1021/jm060470p | Mus musculus | 2 |
| 16913722 | 10.1021/jm060470p | L6 | 1 |
| 16913722 | 10.1021/jm060470p | Plasmodium falciparum | 1 |
| 16913722 | 10.1021/jm060470p | Trypanosoma brucei rhodesiense | 1 |
Data from ChEMBL 36 via Core Engine