Compound Detail
CHEMBL215714
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL215714 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BSPLICRWQBKOHH-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
1
PK Parameters
4
Publications
0
Known Names
Molecular Properties
392.4
MW (Da)
4.11
ALogP
4
HBA
4
HBD
90.2
PSA (Ų)
0.29
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| L6 CHEMBL614793 | IC50 | 5.07 | 5.07 | 8500.0 | 1 |
Pharmacokinetic Data
| Parameter | Value | Units | Species |
|---|---|---|---|
| T1/2 | 1.5 | hr | Mus musculus |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| L6 | IC50 | = | 8500.0 | nM | 5.07 | Cytotoxicity against rat L6 cells | 16913722 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16913722 | 10.1021/jm060470p | Mus musculus | 3 |
| 16913722 | 10.1021/jm060470p | L6 | 1 |
| 16913722 | 10.1021/jm060470p | Plasmodium falciparum | 1 |
| 16913722 | 10.1021/jm060470p | Trypanosoma brucei rhodesiense | 1 |
Data from ChEMBL 36 via Core Engine