Compound Detail
CHEMBL215898
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Basic Information
| ChEMBL ID | CHEMBL215898 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RFSBLJQVMPYUFZ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
446.6
MW (Da)
5.75
ALogP
4
HBA
0
HBD
42.0
PSA (Ų)
0.38
QED
1
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Melanin-concentrating hormone receptor 1 CHEMBL344 | Ki | 6.6 | 6.6 | 251.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Melanin-concentrating hormone receptor 1 | Ki | = | 251.19 | nM | 6.6 | Displacement of radiolabeled iodo-MCH from human MCHR1 expressed in HEK293 cells | 16839761 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16839761 | 10.1016/j.bmcl.2006.06.056 | Melanin-concentrating hormone receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine