Compound Detail
CHEMBL2164024
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Basic Information
| ChEMBL ID | CHEMBL2164024 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PMSTUSHNMMAWCI-UXXRCYHCSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
289.4
MW (Da)
0.54
ALogP
5
HBA
5
HBD
93.0
PSA (Ų)
0.40
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Lysosomal alpha-glucosidase CHEMBL1667668 | EC50 | 5.16 | 5.16 | 7000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Lysosomal alpha-glucosidase | EC50 | = | 7000.0 | nM | 5.16 | Enzyme Activity Assay: Cells were washed two times with 200 μL dPBS followed by ... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22762530 | 10.1021/jm3006178 | Lysosomal acid glucosylceramidase | 1 |
Data from ChEMBL 36 via Core Engine