Compound Detail
CHEMBL216420
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COc1cc(CCC(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@H](C)C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N2CCC[C@@H]2CN[C@@H](Cc2ccccc2)C(N)=O)C(C)C)cc(OC)c1OC
Basic Information
| ChEMBL ID | CHEMBL216420 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AXOIFGMCEYFOMU-IWKRFJIRSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
1171.4
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 9.34
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NIH3T3 CHEMBL614822 | IC50 | 9.34 | 9.34 | 0.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NIH3T3 | IC50 | = | 0.46 | nM | 9.34 | The ability of the peptide to inhibit the binding of 10 pM [125I]gastrin releasi... | 8120863 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8120863 | 10.1021/jm00030a002 | NIH3T3 | 2 |
| 8120863 | 10.1021/jm00030a002 | Gastrin-releasing peptide receptor | 1 |
Data from ChEMBL 36 via Core Engine