Compound Detail
CHEMBL2170963
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2170963 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UDPWSNFKUBMCKI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
322.3
MW (Da)
2.30
ALogP
7
HBA
0
HBD
78.1
PSA (Ų)
0.57
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.13
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatocyte growth factor receptor CHEMBL3717 | Ki | 5.13 | 5.13 | 7390.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatocyte growth factor receptor | Ki | = | 7390.0 | nM | 5.13 | Competitive inhibition of N-terminal His6-tagged recombinant human c-MET (974 to... | 22924734 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22924734 | 10.1021/jm300967g | Hepatocyte growth factor receptor | 2 |
| 22924734 | 10.1021/jm300967g | Hepatocyte | 1 |
| 22924734 | 10.1021/jm300967g | Liver microsomes | 1 |
Data from ChEMBL 36 via Core Engine