Compound Detail
CHEMBL2178855
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Basic Information
| ChEMBL ID | CHEMBL2178855 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IWVUOCJAPYWQIA-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
287.3
MW (Da)
4.12
ALogP
4
HBA
0
HBD
58.8
PSA (Ų)
0.73
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Macrophage migration inhibitory factor homologue CHEMBL2176864 | Ki | 5.8 | 5.8 | 1600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Macrophage migration inhibitory factor homologue | Ki | = | 1600.0 | nM | 5.8 | Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia col... | 23067344 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23067344 | 10.1021/jm301269s | Macrophage migration inhibitory factor homologue | 1 |
Data from ChEMBL 36 via Core Engine