Macrophage migration inhibitory factor homologue · SINGLE PROTEIN · Plasmodium falciparum (isolate 3D7)
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As of 2026-09-14Protein identity stays anchored to UniProt Q8I5C5. Use UniProt Q8I5C5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8I5C5 as the stable identity anchor, then attach disease evidence before program review.
L-dopachrome isomerase
Review this target as Macrophage migration inhibitory factor homologue, mapped to UniProt Q8I5C5. ChEMBL maps the protein component as L-dopachrome isomerase. Sequence length is 116 aa.
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This review treats Macrophage migration inhibitory factor homologue as ChEMBL target CHEMBL2176864, mapped to UniProt Q8I5C5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Macrophage migration inhibitory factor homologue |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum (isolate 3D7) |
| UniProt | Q8I5C5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | L-dopachrome isomerase |
| UniProt Accession | Q8I5C5 |
| Component Type | Protein |
| Sequence Length | 116 aa |
L-dopachrome isomerase
Review this target as Macrophage migration inhibitory factor homologue, mapped to UniProt Q8I5C5. ChEMBL maps the protein component as L-dopachrome isomerase. Sequence length is 116 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2178862 | 7.42 | Ki | 38.0 | Preclinical |
| CHEMBL2178856 | 7.41 | Ki | 39.0 | Preclinical |
| CHEMBL2178851 | 7.37 | Ki | 43.0 | Preclinical |
| CHEMBL2178843 | 6.43 | Ki | 370.0 | Preclinical |
| CHEMBL2178861 | 6.43 | Ki | 370.0 | Preclinical |
| CHEMBL2178849 | 5.92 | Ki | 1200.0 | Preclinical |
| CHEMBL2178855 | 5.8 | Ki | 1600.0 | Preclinical |
| CHEMBL2178846 | 5.58 | Ki | 2600.0 | Preclinical |
| CHEMBL2178858 | 5.52 | Ki | 3000.0 | Preclinical |
| CHEMBL2178852 | 5.26 | Ki | 5500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 31 | 5.3 |