Compound Detail
CHEMBL219839
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL219839 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ONSSSVJVIDXYFQ-SFHVURJKSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
349.4
MW (Da)
2.43
ALogP
3
HBA
3
HBD
95.1
PSA (Ų)
0.61
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.39
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Type-2 angiotensin II receptor CHEMBL4607 | Ki | 7.39 | 7.39 | 40.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Type-2 angiotensin II receptor | Ki | = | 40.6 | nM | 7.39 | Displacement of [125I]Ang2 from AT2 receptor in pig uterus myometrial membrane | 17358051 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17358051 | 10.1021/jm0613469 | Angiotensin II receptor (AT-1) type-1 | 1 |
| 17358051 | 10.1021/jm0613469 | Type-2 angiotensin II receptor | 1 |
Data from ChEMBL 36 via Core Engine