Compound Detail
CHEMBL2203530
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Basic Information
| ChEMBL ID | CHEMBL2203530 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RSHXRVOZRSQOPV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
359.4
MW (Da)
3.98
ALogP
3
HBA
2
HBD
74.8
PSA (Ų)
0.58
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine/threonine-protein kinase 33 CHEMBL6005 | IC50 | 6.82 | 6.82 | 150.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Serine/threonine-protein kinase 33 | IC50 | = | 150.0 | nM | 6.82 | Inhibition of N-terminal 6His-tagged full length human recombinant STK33 using m... | 23256033 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23256033 | 10.1021/ml300246r | Unchecked | 2 |
| - | 10.6019/CHEMBL4495565 | SARS-CoV-2 | 2 |
| 23256033 | 10.1021/ml300246r | No relevant target | 1 |
| 23256033 | 10.1021/ml300246r | Serine/threonine-protein kinase 33 | 1 |
| - | 10.6019/CHEMBL4495564 | Replicase polyprotein 1ab | 1 |
Data from ChEMBL 36 via Core Engine