Compound Detail
CHEMBL2203536
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Basic Information
| ChEMBL ID | CHEMBL2203536 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QUKFWKFKTLOOTK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
328.4
MW (Da)
3.60
ALogP
4
HBA
2
HBD
70.7
PSA (Ų)
0.60
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine/threonine-protein kinase 33 CHEMBL6005 | IC50 | 5.8 | 5.8 | 1600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Serine/threonine-protein kinase 33 | IC50 | = | 1600.0 | nM | 5.8 | Inhibition of N-terminal 6His-tagged full length human recombinant STK33 using m... | 23256033 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23256033 | 10.1021/ml300246r | Unchecked | 1 |
| 23256033 | 10.1021/ml300246r | Serine/threonine-protein kinase 33 | 1 |
Data from ChEMBL 36 via Core Engine