Compound Detail
CHEMBL2206284
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Basic Information
| ChEMBL ID | CHEMBL2206284 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SEPYNUDPEWVUGL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
388.4
MW (Da)
1.85
ALogP
7
HBA
0
HBD
85.9
PSA (Ų)
0.52
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Translocator protein CHEMBL4552 | Ki | 7.4 | 7.4 | 40.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Translocator protein | Ki | = | 40.0 | nM | 7.4 | Displacement of [11C]-PK-11195 from TPSO in Sprague-Dawley rat brain homogenate ... | 21790126 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21790126 | 10.1021/jm200516a | No relevant target | 1 |
| 21790126 | 10.1021/jm200516a | Translocator protein | 1 |
Data from ChEMBL 36 via Core Engine