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Quick search ChEMBL 36
Compound Detail

CHEMBL2228445

YADANZIOSIDE D
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COC(=O)[C@]12OC[C@]34[C@H]([C@@H](O)[C@@H]1O)[C@@]1(C)[C@H](O)[C@@H](O)C=C(C)[C@@H]1C[C@H]3OC(=O)[C@H](OC(C)=O)[C@@H]24

Basic Information

ChEMBL ID CHEMBL2228445
Name YADANZIOSIDE D
Phase Preclinical
Structure Type MOL
InChI Key TWCMVXMQHSVIOJ-VGYYKMHRSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

482.5
MW (Da)
-1.55
ALogP
11
HBA
4
HBD
169.1
PSA (Ų)
0.20
QED
1
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C23H30O11
MW 482.48
Aromatic Rings 0
Heavy Atoms 34
NP-Likeness 3.87

Activity Summary

IC50 1 meas. best 5.25

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Tobacco mosaic virus
CHEMBL613818
IC50 5.25 5.25 5660.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Tobacco mosaic virus IC50 = 5660.0 nM 5.25 In vivo antiviral activity against Tobacco mosaic virus strain U1 (TMV) infected... 20050684

Literature References

PubMed DOI Target Context # Activities
20050684 10.1021/jf903434h Tobacco mosaic virus 7

Data from ChEMBL 36 via Core Engine