Compound Detail
CHEMBL2236806
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Basic Information
| ChEMBL ID | CHEMBL2236806 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RCDYAOUWFSXOIH-QGZVFWFLSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
428.5
MW (Da)
3.64
ALogP
5
HBA
2
HBD
66.4
PSA (Ų)
0.56
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein kinase C beta type CHEMBL3045 | IC50 | 7.5 | 7.495 | 32.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein kinase C beta type | IC50 | = | 32.0 | nM | 7.5 | Inhibition of PKCbeta2 (unknown origin) | - |
| Protein kinase C beta type | IC50 | = | 32.36 | nM | 7.49 | Inhibition of PKCbeta2 (unknown origin) | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1007/s00044-010-9439-6 | Protein kinase C beta type | 2 |
Data from ChEMBL 36 via Core Engine