Compound Detail
CHEMBL224054
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Basic Information
| ChEMBL ID | CHEMBL224054 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ISMBJIARGQNLRV-FOCLMDBBSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
364.5
MW (Da)
5.81
ALogP
3
HBA
1
HBD
46.5
PSA (Ų)
0.50
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.55
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.55 | 4.55 | 27900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 27900.0 | nM | 4.55 | Inhibition of IL5 in mouse Y16 cells at 50 uM | 17064909 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17064909 | 10.1016/j.bmc.2006.10.007 | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine