Compound Detail
CHEMBL22868
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Basic Information
| ChEMBL ID | CHEMBL22868 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YAIIFCKGFTZUMI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
281.7
MW (Da)
2.63
ALogP
3
HBA
2
HBD
79.4
PSA (Ų)
0.84
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 4.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate NMDA receptor CHEMBL1907608 | Ki | 4.68 | 4.68 | 20900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate NMDA receptor | Ki | = | 20900.0 | nM | 4.68 | Inhibition of strychnine-insensitive [3H]glycine binding to the N-methyl-D-aspar... | 1849994 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1849994 | 10.1021/jm00108a007 | Glutamate NMDA receptor | 1 |
Data from ChEMBL 36 via Core Engine