Compound Detail
CHEMBL2295995
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Basic Information
| ChEMBL ID | CHEMBL2295995 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YMMXLRZVUVLUMQ-BOPFTXTBSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
397.5
MW (Da)
4.36
ALogP
5
HBA
1
HBD
66.8
PSA (Ų)
0.44
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dual specificity protein phosphatase 26 CHEMBL2295562 | IC50 | 4.52 | 4.52 | 30200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dual specificity protein phosphatase 26 | IC50 | = | 30200.0 | nM | 4.52 | inhibition of Homo sapiens (human) recombinant DUSP26 catalytic domain (61 to 21... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1007/s00044-012-0405-3 | Dual specificity protein phosphatase 26 | 1 |
Data from ChEMBL 36 via Core Engine