Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL2295562 Target Snapshot

Dual specificity protein phosphatase 26 · SINGLE PROTEIN · Homo sapiens

14Compounds
2Assays
0Approved Drugs
14.0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-15

Protein identity stays anchored to UniProt Q9BV47. Use UniProt Q9BV47 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9BV47 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-15
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Dual specificity protein phosphatase 26 as ChEMBL target CHEMBL2295562, mapped to UniProt Q9BV47. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Dual specificity protein phosphatase 26
SINGLE PROTEIN · Homo sapiens
As of 2026-09-15
ChEMBL target ID
CHEMBL2295562
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-15
www.ebi.ac.uk
UniProt accession
Q9BV47
Dual specificity protein phosphatase 26
UniProt accession via ChEMBL component mapping As of 2026-09-15
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-15
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Dual specificity protein phosphatase 26 is the right protein anchor across sources, using UniProt Q9BV47 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelDual specificity protein phosphatase 26
UniProt AccessionQ9BV47
Component TypeProtein
Sequence Length211 aa

Dual specificity protein phosphatase 26

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Dual specificity protein phosphatase 26, mapped to UniProt Q9BV47. Sequence length is 211 aa.

Mapped IDQ9BV47
Review nameDual specificity protein phosphatase 26
OrganismHomo sapiens
Assay Mix

Activity Type Distribution

IC5014.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL2299386 5.05 IC50 8900.0 Preclinical
CHEMBL2299387 4.9 IC50 12500.0 Preclinical
CHEMBL472004 4.78 IC50 16700.0 Preclinical
CHEMBL2299388 4.77 IC50 17000.0 Preclinical
CHEMBL2296000 4.7 IC50 19800.0 Preclinical
CHEMBL2295992 4.65 IC50 22300.0 Preclinical
CHEMBL2295993 4.6 IC50 25100.0 Preclinical
CHEMBL2295994 4.58 IC50 26300.0 Preclinical
CHEMBL2296001 4.57 IC50 26900.0 Preclinical
CHEMBL2295995 4.52 IC50 30200.0 Preclinical
Distribution

pChEMBL Value Distribution

1
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

2
Total Assays
12
Tested Compounds
1
Assay Types
Binding — 2 assays, 12 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 1 11 4.7
single protein format 1 1 4.8

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine