Compound Detail
CHEMBL2298874
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2298874 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LOYJIHSAFJFQBK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
280.3
MW (Da)
2.45
ALogP
3
HBA
1
HBD
66.5
PSA (Ų)
0.86
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 4.74
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sodium channel protein type 2 subunit alpha CHEMBL4187 | Ki | 4.74 | 4.74 | 18270.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Sodium channel protein type 2 subunit alpha | Ki | = | 18270.0 | nM | 4.74 | Binding affinity to Nav 1.2 (unknown origin) | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1007/s00044-012-0256-y | Mus musculus | 2 |
| - | 10.1007/s00044-012-0256-y | Sodium channel protein type 2 subunit alpha | 1 |
Data from ChEMBL 36 via Core Engine