Compound Detail
CHEMBL230081
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Basic Information
| ChEMBL ID | CHEMBL230081 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YJTRJTNNIPXFJB-WJDWOHSUSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
336.4
MW (Da)
3.79
ALogP
2
HBA
3
HBD
82.2
PSA (Ų)
0.74
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 2 CHEMBL279 | IC50 | 7.05 | 7.05 | 90.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 2 | IC50 | = | 90.0 | nM | 7.05 | Inhibition of KDR | 17306530 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17306530 | 10.1016/j.bmcl.2007.01.089 | Vascular endothelial growth factor receptor 2 | 1 |
Data from ChEMBL 36 via Core Engine