Compound Detail
CHEMBL2313155
PYRAZOSULFURON ETHYL Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL2313155 |
| Name | PYRAZOSULFURON ETHYL |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BGNQYGRXEXDAIQ-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
15
Publications
0
Known Names
Molecular Properties
414.4
MW (Da)
-0.09
ALogP
11
HBA
2
HBD
163.6
PSA (Ų)
0.59
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 7.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Acetolactate synthase catalytic subunit, mitochondrial CHEMBL1075095 | Ki | 7.5 | 7.5 | 32.0 | 1 |
| Unchecked CHEMBL612545 | Ki | 7.18 | 7.18 | 66.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Acetolactate synthase catalytic subunit, mitochondrial | Ki | = | 32.0 | nM | 7.5 | Inhibition of Saccharomyces cerevisiae acetohydroxyacid synthase by colorimetric... | 23237384 |
| Unchecked | Ki | = | 66.0 | nM | 7.18 | Inhibition of Candida albicans acetohydroxyacid synthase catalytic domain expres... | 23237384 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1584/jpestics.15.531 | Oryza sativa | 13 |
| - | 10.1584/jpestics.15.531 | Pontederia vaginalis | 9 |
| - | 10.1584/jpestics.15.531 | Schoenoplectiella juncoides | 9 |
| - | 10.1584/jpestics.15.531 | Echinochloa crus-galli | 9 |
| - | 10.1584/jpestics.15.531 | Cyperus serotinus | 8 |
| - | 10.1584/jpestics.15.531 | Sagittaria pygmaea | 8 |
| - | 10.1584/jpestics.15.531 | unidentified | 5 |
| - | 10.1584/jpestics.15.531 | Eleocharis kuroguwai | 2 |
| - | 10.1584/jpestics.15.531 | Alisma canaliculatum | 2 |
| - | 10.1584/jpestics.15.531 | Unchecked | 1 |
| - | 10.1584/jpestics.15.531 | Rotala indica | 1 |
| 23237384 | 10.1021/jm301501k | Saccharomyces cerevisiae | 1 |
| 23237384 | 10.1021/jm301501k | Candida albicans | 1 |
| 23237384 | 10.1021/jm301501k | Acetolactate synthase catalytic subunit, mitochondrial | 1 |
| 23237384 | 10.1021/jm301501k | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine