Acetolactate synthase catalytic subunit, mitochondrial · SINGLE PROTEIN · Saccharomyces cerevisiae S288c
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As of 2026-09-14Protein identity stays anchored to UniProt P07342. Use UniProt P07342 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P07342 as the stable identity anchor, then attach disease evidence before program review.
Acetolactate synthase catalytic subunit, mitochondrial
Review this target as Acetolactate synthase catalytic subunit, mitochondrial, mapped to UniProt P07342. Sequence length is 687 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Acetolactate synthase catalytic subunit, mitochondrial as ChEMBL target CHEMBL1075095, mapped to UniProt P07342. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Acetolactate synthase catalytic subunit, mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
| UniProt | P07342 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Acetolactate synthase catalytic subunit, mitochondrial |
| UniProt Accession | P07342 |
| Component Type | Protein |
| Sequence Length | 687 aa |
Acetolactate synthase catalytic subunit, mitochondrial
Review this target as Acetolactate synthase catalytic subunit, mitochondrial, mapped to UniProt P07342. Sequence length is 687 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1231791 | 8.48 | Ki | 3.3 | Preclinical |
| CHEMBL2313154 | 8.36 | Ki | 4.4 | Preclinical |
| CHEMBL2313155 | 7.5 | Ki | 32.0 | Preclinical |
| CHEMBL513261 | 7.29 | Ki | 50.8 | Preclinical |
| CHEMBL2313153 | 7.19 | Ki | 64.0 | Preclinical |
| CHEMBL1229721 | 6.9 | Ki | 127.0 | Preclinical |
| CHEMBL331627 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL1885280 | 6.46 | Ki | 346.0 | Preclinical |
| CHEMBL1229780 | 6.4 | Ki | 400.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 9 | 7.2 |