Compound Detail
CHEMBL1229780
TRIBENURON METHYL Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1229780 |
| Name | TRIBENURON METHYL |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VLCQZHSMCYCDJL-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
9
Publications
0
Known Names
Molecular Properties
395.4
MW (Da)
0.51
ALogP
9
HBA
1
HBD
140.7
PSA (Ų)
0.72
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 6.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Acetolactate synthase, chloroplastic CHEMBL4263 | Ki | 6.6 | 6.6 | 253.0 | 1 |
| Acetolactate synthase catalytic subunit, mitochondrial CHEMBL1075095 | Ki | 6.4 | 6.4 | 400.0 | 1 |
| Unchecked CHEMBL612545 | Ki | 5.79 | 5.79 | 1637.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Acetolactate synthase, chloroplastic | Ki | = | 253.0 | nM | 6.6 | Inhibition of Arabidopsis thaliana AHAS expressed in Escherichia coli strain BL2... | 16407096 |
| Acetolactate synthase catalytic subunit, mitochondrial | Ki | = | 400.0 | nM | 6.4 | Inhibition of Saccharomyces cerevisiae acetohydroxyacid synthase by colorimetric... | 23237384 |
| Unchecked | Ki | = | 1637.0 | nM | 5.79 | Inhibition of Candida albicans acetohydroxyacid synthase catalytic domain expres... | 23237384 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21717566 | 10.1002/ps.2231 | Bifora radians | 6 |
| - | 10.6019/CHEMBL4495565 | SARS-CoV-2 | 2 |
| 19117417 | 10.1021/jf802649w | Amaranthus tricolor | 1 |
| 16407096 | 10.1073/pnas.0508701103 | Acetolactate synthase, chloroplastic | 1 |
| 23237384 | 10.1021/jm301501k | Saccharomyces cerevisiae | 1 |
| 23237384 | 10.1021/jm301501k | Candida albicans | 1 |
| 23237384 | 10.1021/jm301501k | Acetolactate synthase catalytic subunit, mitochondrial | 1 |
| 23237384 | 10.1021/jm301501k | Unchecked | 1 |
| - | 10.6019/CHEMBL4495564 | Replicase polyprotein 1ab | 1 |
Data from ChEMBL 36 via Core Engine