Compound Detail
CHEMBL23134
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL23134 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BKPSJOSKWKTWAG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
195.6
MW (Da)
2.52
ALogP
1
HBA
2
HBD
53.1
PSA (Ų)
0.73
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate NMDA receptor CHEMBL1907608 | Ki | 5.0 | 5.0 | 10000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate NMDA receptor | Ki | = | 10000.0 | nM | 5.0 | Inhibition of strychnine-insensitive [3H]glycine binding to the N-methyl-D-aspar... | 1849994 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1849994 | 10.1021/jm00108a007 | Glutamate NMDA receptor | 1 |
| 15115392 | 10.1021/jm0305117 | NS3 | 1 |
| 28283335 | 10.1016/j.bmc.2017.02.035 | Eukaryotic initiation factor 4A-III | 1 |
Data from ChEMBL 36 via Core Engine