Compound Detail
CHEMBL2314421
[18F]FLUSPIDINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL2314421 |
| Name | [18F]FLUSPIDINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LDFPQKADFLEDQV-ONBQKKEBSA-N |
| Parent Compound | CHEMBL1645202 |
| Active Moiety | CHEMBL1645202 |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
1
Known Names
Molecular Properties
325.4
MW (Da)
4.61
ALogP
2
HBA
0
HBD
12.5
PSA (Ų)
0.81
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 6.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Vesicular acetylcholine transporter CHEMBL4767 | Ki | 6.68 | 6.68 | 211.0 | 1 |
| Emopamil-binding protein-like CHEMBL2311238 | Ki | 5.85 | 5.85 | 1400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Vesicular acetylcholine transporter | Ki | = | 211.0 | nM | 6.68 | Binding affinity to VAChT (unknown origin) | 23199475 |
| Emopamil-binding protein-like | Ki | = | 1400.0 | nM | 5.85 | Binding affinity to emopamil binding protein (unknown origin) | 23199475 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23199475 | 10.1016/j.bmc.2012.10.038 | Brain | 1 |
| 23199475 | 10.1016/j.bmc.2012.10.038 | Emopamil-binding protein-like | 1 |
| 23199475 | 10.1016/j.bmc.2012.10.038 | Vesicular acetylcholine transporter | 1 |
Data from ChEMBL 36 via Core Engine