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Target Snapshot

CHEMBL2311238 Target Snapshot

Emopamil-binding protein-like · SINGLE PROTEIN · Homo sapiens

4Compounds
1Assays
2Approved Drugs
4.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q9BY08. Use UniProt Q9BY08 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9BY08 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Emopamil-binding protein-like as ChEMBL target CHEMBL2311238, mapped to UniProt Q9BY08. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Emopamil-binding protein-like
SINGLE PROTEIN · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL2311238
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q9BY08
Emopamil-binding protein-like
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Emopamil-binding protein-like is the right protein anchor across sources, using UniProt Q9BY08 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelEmopamil-binding protein-like
UniProt AccessionQ9BY08
Component TypeProtein
Sequence Length206 aa

Emopamil-binding protein-like

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Emopamil-binding protein-like, mapped to UniProt Q9BY08. Sequence length is 206 aa.

Mapped IDQ9BY08
Review nameEmopamil-binding protein-like
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

2
Approved
Assay Mix

Activity Type Distribution

KI4.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL2314420 8.76 Ki 1.72 Preclinical
CHEMBL83 8.55 Ki 2.8 Approved
CHEMBL422 8.41 Ki 3.9 Approved
CHEMBL2314421 5.85 Ki 1400.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
1
5.5
0
6.0
0
6.5
0
7.0
0
7.5
1
8.0
2
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

TAMOXIFEN
CHEMBL83
Approved 1977
TRIFLUOPERAZINE
CHEMBL422
Approved 1959
Assay Landscape

Assay Landscape

1
Total Assays
4
Tested Compounds
1
Assay Types
Binding — 1 assays, 4 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 1 4 7.9

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine