Compound Detail
CHEMBL2326504
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2326504 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QSIOZNXDXNWPNX-AKEJEFCPSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
279.3
MW (Da)
-0.17
ALogP
7
HBA
3
HBD
110.1
PSA (Ų)
0.66
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatitis B virus CHEMBL613497 | EC50 | 6.26 | 6.215 | 548.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatitis B virus | EC50 | = | 548.0 | nM | 6.26 | Antiviral activity against wild type Hepatitis B virus infected in human HuH7 ce... | 23237841 |
| Hepatitis B virus | EC50 | = | 670.0 | nM | 6.17 | Antiviral activity against entecavir-resistant Hepatitis B virus harboring L180M... | 23237841 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23237841 | 10.1016/j.bmcl.2012.11.027 | Hepatitis B virus | 3 |
| 23237841 | 10.1016/j.bmcl.2012.11.027 | HepG2 | 1 |
| 23237841 | 10.1016/j.bmcl.2012.11.027 | Huh-7 | 1 |
Data from ChEMBL 36 via Core Engine