Compound Detail
CHEMBL2326846
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Basic Information
| ChEMBL ID | CHEMBL2326846 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MEFLMETXGJZGFU-IBGZPJMESA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
407.2
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 7.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | Ki | 7.43 | 7.375 | 37.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | Ki | = | 37.0 | nM | 7.43 | Inhibition of wild type Beta-lactamase SHV-1 in Escherichia coli DH10B by Henri-... | 23252553 |
| Unchecked | Ki | = | 48.0 | nM | 7.32 | Inhibition of Beta-lactamase SHV-1 K234R protein mutant in Escherichia coli DH10... | 23252553 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23252553 | 10.1021/jm301490d | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine