Compound Detail
CHEMBL2333218
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2333218 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | TVTANTTXMLBIDA-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
336.4
MW (Da)
3.55
ALogP
4
HBA
0
HBD
51.1
PSA (Ų)
0.84
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Telomerase reverse transcriptase CHEMBL2916 | IC50 | 4.17 | 4.17 | 68233.9 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Telomerase reverse transcriptase | IC50 | = | 68300.0 | nM | 4.17 | Inhibition of telomerase in human SGC7901 cells by TRAP assay | 23312949 |
| Telomerase reverse transcriptase | IC50 | = | 68233.87 | nM | 4.17 | Inhibition of telomerase in human SGC7901 cells by TRAP assay | 23312949 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23312949 | 10.1016/j.bmcl.2012.12.010 | Telomerase reverse transcriptase | 2 |
Data from ChEMBL 36 via Core Engine