Compound Detail
CHEMBL233375
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL233375 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MHRJJGJJVMGLRQ-UITAMQMPSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
251.3
MW (Da)
1.72
ALogP
5
HBA
2
HBD
75.6
PSA (Ų)
0.78
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.01
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosinase CHEMBL3318 | IC50 | 5.01 | 5.01 | 9870.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tyrosinase | IC50 | = | 9870.0 | nM | 5.01 | Inhibition of mushroom tyrosinase activity using L-tyrosine as substrate after 3... | 22301213 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22301213 | 10.1016/j.ejmech.2012.01.019 | Tyrosinase | 7 |
| 22301213 | 10.1016/j.ejmech.2012.01.019 | B16 | 2 |
| 17512196 | 10.1016/j.bmcl.2007.04.109 | Aldo-keto reductase family 1 member B1 | 1 |
Data from ChEMBL 36 via Core Engine