Compound Detail
CHEMBL233616
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL233616 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PISCDHVNCKBABZ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
318.4
MW (Da)
4.11
ALogP
4
HBA
0
HBD
55.1
PSA (Ų)
0.66
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.09
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Metabotropic glutamate receptor 5 CHEMBL2564 | IC50 | 7.09 | 7.09 | 82.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Metabotropic glutamate receptor 5 | IC50 | = | 82.0 | nM | 7.09 | Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of ... | 17590335 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17590335 | 10.1016/j.bmcl.2007.06.030 | Metabotropic glutamate receptor 5 | 1 |
Data from ChEMBL 36 via Core Engine