Compound Detail
CHEMBL2346816
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Basic Information
| ChEMBL ID | CHEMBL2346816 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JSLPGJYKUGNXMI-JSSTZBRYSA-N |
| Parent Compound | CHEMBL2365738 |
| Active Moiety | CHEMBL2365738 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
201.2
MW (Da)
0.98
ALogP
2
HBA
4
HBD
90.0
PSA (Ų)
0.33
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate [NMDA] receptor CHEMBL2094124 | IC50 | 4.3 | 4.3 | 50118.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate [NMDA] receptor | IC50 | = | 50118.72 | nM | 4.3 | Displacement of [3H]MK-801 from NMDA receptor complex (unknown origin) after 40 ... | 23465801 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23465801 | 10.1016/j.bmc.2013.01.051 | Glutamate [NMDA] receptor | 1 |
Data from ChEMBL 36 via Core Engine