Compound Detail
CHEMBL2349337
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2349337 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | TZWVRQVXJIDRAG-HNNXBMFYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
409.5
MW (Da)
4.11
ALogP
8
HBA
3
HBD
97.0
PSA (Ų)
0.31
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| CX3C chemokine receptor 1 CHEMBL4843 | Ki | 6.66 | 6.66 | 220.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| CX3C chemokine receptor 1 | Ki | = | 220.0 | nM | 6.66 | Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells afte... | 23516963 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23516963 | 10.1021/jm3012273 | C-X-C chemokine receptor type 2 | 1 |
| 23516963 | 10.1021/jm3012273 | CX3C chemokine receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine