Compound Detail
CHEMBL2362410
LANDIOLOL HYDROCHLORIDE 💊 Approved Drug
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💊 Approved Drug
CC1(C)OC[C@@H](COC(=O)CCc2ccc(OC[C@@H](O)CNCCNC(=O)N3CCOCC3)cc2)O1.Cl
Basic Information
| ChEMBL ID | CHEMBL2362410 |
| Name | LANDIOLOL HYDROCHLORIDE |
| Phase | Approved |
| Structure Type | MOL |
| InChI Key | DLPGJHSONYLBKP-IKGOIYPNSA-N |
| Therapeutic | ✓ Yes |
| Parent Compound | CHEMBL1742466 |
| Active Moiety | CHEMBL1742466 |
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
5
Known Names
3
Indications
1
Mechanisms
Molecular Properties
509.6
MW (Da)
0.69
ALogP
9
HBA
3
HBD
127.8
PSA (Ų)
0.26
QED
1
Ro5 Violations
13
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| First Approval | 2024 |
| Availability | Prescription |
| Chirality | Single Enantiomer |
Mechanism of Action
| Mechanism | Action Type | Target | Direct | Efficacy |
|---|---|---|---|---|
| Beta-1 adrenergic receptor antagonist | ANTAGONIST | Beta-1 adrenergic receptor | ✓ | ✓ |
Indications
Atrial Fibrillation Atrial Flutter Tachycardia, Supraventricular
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.6019/CHEMBL4495565 | SARS-CoV-2 | 2 |
| - | 10.21203/rs.3.rs-23951/v1 | SARS-CoV-2 | 1 |
| - | 10.6019/CHEMBL4495564 | Replicase polyprotein 1ab | 1 |
Data from ChEMBL 36 via Core Engine