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Compound Detail

CHEMBL236398

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CC(=O)C1(O)C(c2cc3oc(=O)c4cc(O)c(O)cc4c3c(=O)o2)=Cc2cc(O)c(O)cc21

Basic Information

ChEMBL ID CHEMBL236398
Phase Preclinical
Structure Type MOL
InChI Key NITFEFGLVNCSOC-UHFFFAOYSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

450.4
MW (Da)
2.05
ALogP
10
HBA
5
HBD
178.6
PSA (Ų)
0.22
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C23H14O10
MW 450.36
Aromatic Rings 4
Heavy Atoms 33
NP-Likeness 1.32

Activity Summary

IC50 1 meas. best 4.04

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
NON-PROTEIN TARGET
CHEMBL3879801
IC50 4.04 4.04 90800.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
NON-PROTEIN TARGET IC50 = 90800.0 nM 4.04 Antioxidant activity assessed as superoxide radical scavenging activity by xanth... 17980585

Literature References

PubMed DOI Target Context # Activities
17980585 10.1016/j.bmcl.2007.10.072 Unchecked 2
17980585 10.1016/j.bmcl.2007.10.072 NON-PROTEIN TARGET 1

Data from ChEMBL 36 via Core Engine