Compound Detail
CHEMBL2365743
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Basic Information
| ChEMBL ID | CHEMBL2365743 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PDWJALXSRRSUHR-LFYBBSHMSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
196.6
MW (Da)
1.16
ALogP
2
HBA
3
HBD
74.3
PSA (Ų)
0.38
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 4.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | Kd | 4.64 | 4.64 | 23000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | Kd | = | 23000.0 | nM | 4.64 | Binding affinity to N-terminal MBP-fused C-terminal His6 tagged-PPP1R15A (340 to... | 32460492 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 32460492 | 10.1021/acs.jmedchem.0c00249 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine